Enabling The Oral Absorption of Drug Molecules

Dr. Roy Haskell, PhD

Executive Director, Formulation R&D

Arvinas, New Haven CT

The weak overlap between the physicochemical space that affords therapeutic utility and that which permits effective oral absorption is well-known and much-discussed.  In addition to enabling the presenter’s and many other physical scientists’ employment in the pharmaceutical industry, it is also responsible for the development of solubilization technologies capable of producing systemic exposure of lipophilic, insoluble compounds.  Nanoparticles, self-emulsifying lipid systems, and amorphous dispersions are considered increasingly mainstream technologies to bring such molecules to the marketplace.  This presentation will discuss the basics of these approaches as well as the strategies used for their implementation in compound design, selection, and development.  This will be done through the presentation of background material and specific case studies of their use and just as importantly, their misuse.
 

Eli’s Restaurant, Hamden

2392 Whitney Ave Hamden, CT 06518

Networking:     6:00 – 6:45pm

Buffet Dinner:  6:45 – 7:45pm

Presentation:  7:45 – 9:00pm

RSVP online at: https://goo.gl/forms/J5c8h72d1CoFdT1p2

Remember if you reserve a spot at dinner you will be charged whether you show up or not!